Protein Info for SMc00347 in Sinorhizobium meliloti 1021

Annotation: nucleoside diphosphate kinase regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 135 PF14760: Rnk_N" amino acids 11 to 50 (40 residues), 44.6 bits, see alignment E=1.6e-15 PF01272: GreA_GreB" amino acids 57 to 130 (74 residues), 61.8 bits, see alignment E=4.7e-21

Best Hits

KEGG orthology group: K06140, regulator of nucleoside diphosphate kinase (inferred from 100% identity to smk:Sinme_3597)

Predicted SEED Role

"Regulator of nucleoside diphosphate kinase" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92SU5 at UniProt or InterPro

Protein Sequence (135 amino acids)

>SMc00347 nucleoside diphosphate kinase regulator (Sinorhizobium meliloti 1021)
MADKTTRKKLPSIVINAEDHARLTAIASSALDRVPDVAEALLSELDRARIAAPGKLPKDS
VQMGSTVAFDADNGFAKEVRLVYPGEADIEAGKISVLTPIGAALIGLSVGQSIDWVDRAG
KVHRMTIRSVMPQAD