Protein Info for SMc00301 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 130 TIGR01997: FeS assembly scaffold SufA" amino acids 4 to 111 (108 residues), 177.3 bits, see alignment E=7.7e-57 PF01521: Fe-S_biosyn" amino acids 6 to 107 (102 residues), 66.1 bits, see alignment E=1.5e-22 TIGR00049: iron-sulfur cluster assembly accessory protein" amino acids 7 to 109 (103 residues), 113.9 bits, see alignment E=3.8e-37

Best Hits

Swiss-Prot: 43% identical to Y484_RICPR: Uncharacterized protein RP484 (RP484) from Rickettsia prowazekii (strain Madrid E)

KEGG orthology group: K13628, iron-sulfur cluster assembly protein (inferred from 100% identity to smk:Sinme_1634)

Predicted SEED Role

"Iron binding protein SufA for iron-sulfur cluster assembly"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92PL4 at UniProt or InterPro

Protein Sequence (130 amino acids)

>SMc00301 hypothetical protein (Sinorhizobium meliloti 1021)
MGFAVMSLTDAAASRVRSIVENAGGEAKGIRISIKKGGCAGMEYAVDLVSEPNSKDDLIE
QQGAKVWVAPEAVLYLLGTQMDFETTTLRSGFTFNNPNQTSACGCGESVELKPADLAALA
ERGDAVVRAS