Protein Info for SMc00143 in Sinorhizobium meliloti 1021

Annotation: molybdopterin-guanine dinucleotide biosynthesis protein MobA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 TIGR02665: molybdenum cofactor guanylyltransferase" amino acids 12 to 204 (193 residues), 215.1 bits, see alignment E=4.3e-68 PF12804: NTP_transf_3" amino acids 13 to 175 (163 residues), 130.1 bits, see alignment E=4.4e-42

Best Hits

Swiss-Prot: 100% identical to MOBA_RHIME: Molybdenum cofactor guanylyltransferase (mobA) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03752, molybdopterin-guanine dinucleotide biosynthesis protein A (inferred from 100% identity to smk:Sinme_1771)

Predicted SEED Role

"Molybdopterin-guanine dinucleotide biosynthesis protein MobA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92PB2 at UniProt or InterPro

Protein Sequence (218 amino acids)

>SMc00143 molybdopterin-guanine dinucleotide biosynthesis protein MobA (Sinorhizobium meliloti 1021)
MTGAPSHATFPPAVILAGGLSSRMGRPKAGLVLGGRSMLTRVIERLRPQVAGIAINLNAD
PDPASAFGLEVVPDTIPGFVGPLAGILAAMRHTVRKSPGASHVLTVPVDTPLFPKSLAAR
LKTAITSGGEIAVAFSAGEMHPLFALWPVALADDLEAWIHADEKRRVRAFIARHESATVE
FPLIPTAAGPLDPFFNINTPEELRQAEAWLPYLEDREP