Protein Info for SMa2383 in Sinorhizobium meliloti 1021

Annotation: oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 PF08240: ADH_N" amino acids 28 to 87 (60 residues), 37.2 bits, see alignment E=3.4e-13 PF00107: ADH_zinc_N" amino acids 151 to 258 (108 residues), 72.8 bits, see alignment E=4.1e-24 PF13602: ADH_zinc_N_2" amino acids 184 to 320 (137 residues), 70.5 bits, see alignment E=4.3e-23

Best Hits

KEGG orthology group: K00344, NADPH2:quinone reductase [EC: 1.6.5.5] (inferred from 100% identity to sme:SMa2383)

Predicted SEED Role

"Quinone oxidoreductase (EC 1.6.5.5)" in subsystem ZZ gjo need homes (EC 1.6.5.5)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.5

Use Curated BLAST to search for 1.6.5.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92XG6 at UniProt or InterPro

Protein Sequence (322 amino acids)

>SMa2383 oxidoreductase (Sinorhizobium meliloti 1021)
MKAVVMKEVGGTDVMEFVDRPEPVARPAHVVVEVAAAGVNFMDIGVRQGMAWTDIPNPKV
LGVEGAGRVLAVGDGTGEFAVGDRVAWVYAPGSYAQRQSIPAASLVKIPDTVDDRTAAST
MMQGLTASHFATDFYPVQPGDIALVHAAAGGVGLLLTQIIRLRGGRVIGRVSSEDKVAIA
RKAGAEHVIVDTDGRFADEVLRLTGGEGVNVVYDGSGPKTFKGSIEALRRSGTFCWYGPV
LGGPGPLEIMNLPKSIKIGYATFMDHIHTRELLLDRTKQLFDWIEDGSITVTIGETYRLA
DAAGAHAAMASRATTGKLLLIP