Protein Info for SMa1798 in Sinorhizobium meliloti 1021

Annotation: Kup2 potassium uptake protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 transmembrane" amino acids 18 to 39 (22 residues), see Phobius details amino acids 59 to 82 (24 residues), see Phobius details amino acids 108 to 128 (21 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 172 to 194 (23 residues), see Phobius details amino acids 214 to 240 (27 residues), see Phobius details amino acids 253 to 273 (21 residues), see Phobius details amino acids 293 to 320 (28 residues), see Phobius details amino acids 345 to 366 (22 residues), see Phobius details amino acids 372 to 391 (20 residues), see Phobius details amino acids 401 to 424 (24 residues), see Phobius details amino acids 431 to 448 (18 residues), see Phobius details PF02705: K_trans" amino acids 23 to 555 (533 residues), 676.4 bits, see alignment E=1.4e-207

Best Hits

Swiss-Prot: 100% identical to KUP2_RHIME: Probable potassium transport system protein kup 2 (kup2) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 100% identity to smk:Sinme_6201)

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Y93 at UniProt or InterPro

Protein Sequence (633 amino acids)

>SMa1798 Kup2 potassium uptake protein (Sinorhizobium meliloti 1021)
MADSLDHAPAQANNLPQFLALTIGAIGVVYGDIGTSPLYAFREALRPFGPGGVGRDEVIG
LVSLVLWTLTAIVTIKYVLFLLRADNDGEGGTLSLLALLLKKGTKYPVLMFFAGVLGAAL
FIGDAMITPALSVLSAVEGLKLVAPALHDYVLPISVVIILLLFAVQSRGTGAVSVFFGPI
TLVWFLMMAAAGVAHIGDDLAILSAFNPLNAIGFLWNAGLIGFIVLGAIFLTVTGAEALY
ADLGHFGRHSIQAAWFAVVFPALALNYLGQGALVLSHPDAISNPFFLMFPNWALLPMVIL
ATAATIIASQSVITGAFSLIRQAIHLGFLPRFEICYTSETQTGQIYLPLVNTILLTGVLA
LMLMFGSSEALAPAYGVSITGAMVIDTILAFEFVRRQWGWPALTAIAVLLPLFNLELVFL
GANLLKVHHGGYVPILIAGTLITMMWTWRKGVSVLREKTARQDIPLSQFMAIVERKSEHA
PVQVPGTAIFLTATPDTTPAVLLHNIKHNHVLHQHNVIMTIKTARVPYVPEKDRYTITKL
SDRFSLLELRFGFMDDQNVSRALARCRKEGFKFEIMSTSFYLGRRKLIADPQSGLPQWQD
KLFIAMADSAIDPTEYFHLPANRVVELGEQVII