Protein Info for SMa1727 in Sinorhizobium meliloti 1021

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00561: Abhydrolase_1" amino acids 60 to 159 (100 residues), 93.3 bits, see alignment E=4e-30 amino acids 217 to 283 (67 residues), 36.2 bits, see alignment E=1.1e-12 PF12146: Hydrolase_4" amino acids 62 to 282 (221 residues), 68.6 bits, see alignment E=1e-22 PF12697: Abhydrolase_6" amino acids 62 to 288 (227 residues), 97.1 bits, see alignment E=4.9e-31 PF01738: DLH" amino acids 234 to 284 (51 residues), 21.7 bits, see alignment 2.7e-08

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMa1727)

Predicted SEED Role

"Small molecule metabolism"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92YD4 at UniProt or InterPro

Protein Sequence (296 amino acids)

>SMa1727 alpha/beta hydrolase (Sinorhizobium meliloti 1021)
MTTTILKLALAVGLLFAAGPGFATEIPVPTQTEWAAAKKTVDLPNGIKLAYSEMGNVEGK
PLLLIHGYTDNSRSWSLVAPYLKNHHIYAIDLRGHGKSSAPECCYTYLDFANDAFLFLEA
MKIEQADVVGHSLGSLAVQMLAAQHPEKVRKVVLISSTLNTGGGPGTWLWDNIKPLQPPI
DPNGKFMTDWYWNPNPVDERFIKPEREESAAVPIHVWKGVLWGTTTGDLGKISSLIKAPV
MIFWGDQDQLMNAPQQAKLKAAFPKARFETFPGAGHNMFWERPEKAAELINSFLSE