Protein Info for SMa1691 in Sinorhizobium meliloti 1021

Annotation: Cation transport ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 484 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 40 to 59 (20 residues), see Phobius details amino acids 71 to 93 (23 residues), see Phobius details amino acids 130 to 155 (26 residues), see Phobius details amino acids 178 to 202 (25 residues), see Phobius details amino acids 238 to 261 (24 residues), see Phobius details amino acids 273 to 293 (21 residues), see Phobius details amino acids 299 to 319 (21 residues), see Phobius details amino acids 326 to 348 (23 residues), see Phobius details amino acids 354 to 373 (20 residues), see Phobius details amino acids 392 to 417 (26 residues), see Phobius details amino acids 421 to 439 (19 residues), see Phobius details amino acids 456 to 482 (27 residues), see Phobius details PF02386: TrkH" amino acids 40 to 476 (437 residues), 205.7 bits, see alignment E=5.5e-65

Best Hits

Swiss-Prot: 43% identical to TRKI_HALED: Trk system potassium uptake protein TrkI (trkI) from Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)

KEGG orthology group: K03498, trk system potassium uptake protein TrkH (inferred from 100% identity to sme:SMa1691)

Predicted SEED Role

"Potassium uptake protein TrkH" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92YF2 at UniProt or InterPro

Protein Sequence (484 amino acids)

>SMa1691 Cation transport ATPase (Sinorhizobium meliloti 1021)
MNASLFRHAMHIAAILGLYLSAAMLIPAMLDLYYGHYDWQVFAAAAFVTSGLSATTFMAT
RGGPPPFSKKFGFLLVNVLWSAFALIGALPLWMSSLDLDFAQALFESVSAITTTGSTVIV
GLDDAPPGILIWRSLICWLGGVGIVVLGLFIIPYLRVGGMSFFKMESSDTNEKPFARLAT
FSRAFFTVYVGITLLCAIGYNLTGMNRFDAINHAMSTVATGGFSTHDASFAYFGSIPLLW
TATFFMTLCSLPFSILIVFVARGRLDALRDPQIFVFLAYLTVFAFSVAIYHRLTNGVEFH
IALAHAFFNFSSILSTAGYMSEDYQLWGPFVVMAAFIATFMGGCSGSTAGGIKAYRFIVL
FNAIHSGLRKLIYPAAVYPVRYGRNSLDADTLRAILLFFVTYILLWIFGSLTMAALGYDF
LTAVSAVITCLSNVGPGLGTLVGPAGNFSTLEDPELYLLSLMMMMGRLEVLTVLVILTPV
FWKQ