Protein Info for SMa1684 in Sinorhizobium meliloti 1021

Annotation: Sensory histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details transmembrane" amino acids 351 to 374 (24 residues), see Phobius details PF00512: HisKA" amino acids 404 to 468 (65 residues), 27.6 bits, see alignment E=2.4e-10 PF02518: HATPase_c" amino acids 515 to 601 (87 residues), 59 bits, see alignment E=6.2e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMa1684)

Predicted SEED Role

"FIG00984882: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92YF5 at UniProt or InterPro

Protein Sequence (627 amino acids)

>SMa1684 Sensory histidine kinase (Sinorhizobium meliloti 1021)
MSLERHWTTRSRQLGRYVVPCCVILGTSAAAPVAALKTGDHVPRVLILYPYDERLAATTA
AGEAIRTRLLQATKARIDLFSEFLDLSRFPEAEHIGRMARYLSAKYADRRPDVVIALGEV
SARFISANRRELAASAKIIVAGFSSSTAEEMDLPNDVVGAFSEFDIVKTAEMARGLQPEA
RHLFIIGGSSEFDRSWLSRARADLAAFSKDYETTYLEDLTIEEFTKVAAEVPRDSIILAL
TILKDRDGRNFMPREAVKQIAETAGAPIYGPYLTYIDYGVVGGSVVTFESLGKTVADLAL
EAVAGKPISNLESRQTYVADARQLERWGLSEKNLPAGAIQMFKEPTFWEQYWLAAVFALA
VITFQGTVIAGLLIERRRRQAAETESRHRLLEVVHLNQSATAGALSASIAHELNQPLGAI
RSNAEAAAVILRSERPDLELIGQILVDIQDDDQRAHDVISRIRGLLKKRSEIDWQEFDLN
DVTTSAIRILRGEAERGSVVVSSSQTSRELPVRADRVHVQQVILNLATNAMDAMLEVITT
EKRLLLETRLTAESKVELSISDTGRDIPDERFASVFEPFYTTKPTGTGLGLSIARAIVET
YARSRPPTVLEAERSFVLCCLSHEMGE