Protein Info for SMa1649 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 79 to 106 (28 residues), see Phobius details amino acids 118 to 139 (22 residues), see Phobius details amino acids 141 to 163 (23 residues), see Phobius details amino acids 196 to 225 (30 residues), see Phobius details amino acids 250 to 273 (24 residues), see Phobius details PF12911: OppC_N" amino acids 16 to 50 (35 residues), 25.9 bits, see alignment 7.3e-10 PF00528: BPD_transp_1" amino acids 97 to 271 (175 residues), 100.6 bits, see alignment E=9.3e-33

Best Hits

Swiss-Prot: 40% identical to NIKC_ECOLI: Nickel transport system permease protein NikC (nikC) from Escherichia coli (strain K12)

KEGG orthology group: K02034, peptide/nickel transport system permease protein (inferred from 100% identity to sme:SMa1649)

MetaCyc: 40% identical to nickel ABC transporter membrane subunit NikC (Escherichia coli K-12 substr. MG1655)
7.2.2.i [EC: 7.2.2.i]; 7.2.2.- [EC: 7.2.2.i]

Predicted SEED Role

"Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.i

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92YH9 at UniProt or InterPro

Protein Sequence (303 amino acids)

>SMa1649 ABC transporter permease (Sinorhizobium meliloti 1021)
MELIMKILTSFSARLNKMPRAALITIGLFVALGTFAPWLAPQDPSAQNLLEAGVGPNGAH
WLGTDHLGRDTFSRLIIAANTSLVSVGSVLAIAMTIGIAMGTIAGYHRGWVDDVLMRVVD
VGLSIPSLIIALAVIGIVGPGYWTMVMALALAWWPMSGRISRAVAVSIMSKPHIEALRVL
GASPWRIYFNHLLPGTIGAVMVYATADAGVAALAVATLSFLGLGIQPPTPEWGQMLVDAL
PYLESDPRQVILPGLALTAAVIGFNTLGESIALNRIPKPLTRRMLAARRIEVAGWAKESI
DAK