Protein Info for SMa1485 in Sinorhizobium meliloti 1021

Annotation: Permease, MFS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 14 to 35 (22 residues), see Phobius details amino acids 56 to 77 (22 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 113 to 132 (20 residues), see Phobius details amino acids 144 to 163 (20 residues), see Phobius details amino acids 171 to 192 (22 residues), see Phobius details amino acids 216 to 237 (22 residues), see Phobius details amino acids 246 to 270 (25 residues), see Phobius details amino acids 278 to 299 (22 residues), see Phobius details amino acids 305 to 327 (23 residues), see Phobius details amino acids 339 to 360 (22 residues), see Phobius details amino acids 366 to 387 (22 residues), see Phobius details PF07690: MFS_1" amino acids 24 to 331 (308 residues), 124.3 bits, see alignment E=2.8e-40

Best Hits

Swiss-Prot: 53% identical to OPDE_PSEAE: Transcription regulatory protein OpdE (opdE) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_6003)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92YQ5 at UniProt or InterPro

Protein Sequence (429 amino acids)

>SMa1485 Permease, MFS (Sinorhizobium meliloti 1021)
MTNPTFGETIVKTAAAWGAGASMALCVAVLIASEFMPVSLLTPIARDLGMSEGEAGQAIS
ISGLFAVLTSLFIAGFTRKIDRKFVLSSFSLMLIVSGLVVSFAPNYTALMVGRALLGVAI
GGFWSMSTAVVMRLLPESAVPEGLALLNAGNAIAATISAPLGSFLGDYIGWRGAFFFVVP
LALIALIGQWTNMPSLPPRNRRATGNVFRLLARRQVALGMTAILLLFMGQFALFTYLRPF
LESAAGFSVSGLSLVLLLMGLAGVAGTWCISRLLVTRLYSIVIAIPLVMAAIALTLMAVG
SKLPVAALLIAWGFFGTAAPVGWGTWLSRVLHDDAEAGGGLQVAVIQFAIAIGAAAGGLL
FDWAGWWSSFAFAAALLLGSSVAAWAASFEWEHSKSNGDPPRSRRGSRSAAPSPGPYCRA
WYGLKRRLT