Protein Info for SMa1374 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 transmembrane" amino acids 31 to 54 (24 residues), see Phobius details amino acids 100 to 124 (25 residues), see Phobius details amino acids 143 to 172 (30 residues), see Phobius details amino acids 218 to 242 (25 residues), see Phobius details amino acids 263 to 286 (24 residues), see Phobius details PF12911: OppC_N" amino acids 25 to 68 (44 residues), 45.3 bits, see alignment 6.4e-16 PF00528: BPD_transp_1" amino acids 115 to 295 (181 residues), 111.6 bits, see alignment E=3.8e-36

Best Hits

Swiss-Prot: 42% identical to DPPC_ECO57: Dipeptide transport system permease protein DppC (dppC) from Escherichia coli O157:H7

KEGG orthology group: K02034, peptide/nickel transport system permease protein (inferred from 100% identity to smk:Sinme_5944)

MetaCyc: 42% identical to dipeptide ABC transporter membrane subunit DppC (Escherichia coli K-12 substr. MG1655)
ABC-8-RXN [EC: 7.4.2.9]

Predicted SEED Role

"Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92YW0 at UniProt or InterPro

Protein Sequence (319 amino acids)

>SMa1374 ABC transporter permease (Sinorhizobium meliloti 1021)
MAASASAASPTPVGTRVPRGRISELWHDKTAAIGLALILLIVFLALFAPLIAPYDPAAQS
IMARLKPPVWMERGTWEHLLGTDNLGRDVLSRIIWGARATLTIGAVTCLLAATLGTVIGL
WAGFMGGRTDSILMRLVDIQVSFPGILLILLVVAVLGPGVWTLVAVLSVTNWMVYARLVR
GIVSSTRQTPYVEAAEVIGCRPARVIFRHILPNIVSPLMTLAILEFTNIVLAEAAVSFLG
FGVQPPATSWGLDVASGRDYLFIAWWLVTFPGLAIVATVLSINLFANWLRVTTDPEEREK
RFARAEAARRRRGRRRAEA