Protein Info for SMa1319 in Sinorhizobium meliloti 1021

Annotation: VirB2 type IV secretion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 99 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 49 to 69 (21 residues), see Phobius details amino acids 77 to 97 (21 residues), see Phobius details PF04956: TrbC" amino acids 4 to 96 (93 residues), 88.6 bits, see alignment E=1.3e-29

Best Hits

Swiss-Prot: 41% identical to VIRB2_BARHE: Type IV secretion system protein virB2 (virB2) from Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1)

KEGG orthology group: K03197, type IV secretion system protein VirB2 (inferred from 99% identity to smk:Sinme_5907)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92YZ4 at UniProt or InterPro

Protein Sequence (99 amino acids)

>SMa1319 VirB2 type IV secretion protein (Sinorhizobium meliloti 1021)
MTFSSRIRPIAASTVMATAIMVTMVEPAFAQAAGIETVLQNIVDMLTGNIAKLLAVIAVI
VICIAWMFGYMDLRRAGFWIIGIGGIFGATELVNTIVGS