Protein Info for SMa1302 in Sinorhizobium meliloti 1021

Annotation: VirB11-like ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 329 TIGR02788: P-type DNA transfer ATPase VirB11" amino acids 20 to 326 (307 residues), 416.8 bits, see alignment E=2.3e-129 PF00437: T2SSE" amino acids 62 to 311 (250 residues), 100 bits, see alignment E=5.9e-33

Best Hits

Swiss-Prot: 47% identical to VIRBB_BRUSU: Type IV secretion system protein VirB11 (virB11) from Brucella suis biovar 1 (strain 1330)

KEGG orthology group: K03196, type IV secretion system protein VirB11 (inferred from 100% identity to sme:SMa1302)

MetaCyc: 47% identical to P-type DNA transfer ATPase VirB11 (Brucella abortus 2308)
TRANS-RXN-477 [EC: 7.4.2.8]

Predicted SEED Role

No annotation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Z03 at UniProt or InterPro

Protein Sequence (329 amino acids)

>SMa1302 VirB11-like ATPase (Sinorhizobium meliloti 1021)
MTEGADATVVRELLSPFAPFLGDRSLYEVIVNRPGQVLTEGAGGWRTYDLPELSFEKLMR
LARAVASFSHQSIDETRPILSATLPGDERIQIVIPPATTRNTVSITIRKPSSVTFTLNDL
KEREFFSETRSANDGASTRDDGLLALYRAGRFKEFLRHAVISRKNIIISGATGSGKTTLS
KALIKHIPEHERIISIEDTPELIIPQPNHVRLFYSKGAQGLSGAGPKELLESCLRMRPDR
ILLQELRDGTAFYYVRNVNSGHPGSITTVHADSAKLAFQQLTLLVKESAGGRNLDRDDID
KLLKVSIDVIVQCKRIDGRFRATEIYVRA