Protein Info for SMa1210 in Sinorhizobium meliloti 1021

Annotation: nitrogen fixation protein FixH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 167 transmembrane" amino acids 16 to 39 (24 residues), see Phobius details PF05751: FixH" amino acids 13 to 156 (144 residues), 108.1 bits, see alignment E=2.2e-35

Best Hits

Swiss-Prot: 100% identical to FIXH_RHIME: Nitrogen fixation protein FixH (fixH) from Rhizobium meliloti (strain 1021)

KEGG orthology group: None (inferred from 100% identity to sme:SMa1210)

Predicted SEED Role

"Type cbb3 cytochrome oxidase biogenesis protein CcoH" in subsystem Biogenesis of cbb3-type cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P18397 at UniProt or InterPro

Protein Sequence (167 amino acids)

>SMa1210 nitrogen fixation protein FixH (Sinorhizobium meliloti 1021)
MSTATKQRSPKRGFTGWHMVAVMSLFFGTVISVNLVMAWNASRSWSGLVVENTYVASQQF
NGKVAEGRAFQASGIKGRLTTEPGAIRYVLTRNGEPEQKIDKVIAVLKRPVEEHEDLRVE
LHPRGEGAFVLAEELKPGQWIAAMMAMAGDAVVHRQTIRFIAEGRDK