Protein Info for SMa1141 in Sinorhizobium meliloti 1021

Annotation: FNR/CRP family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 PF00027: cNMP_binding" amino acids 36 to 120 (85 residues), 55.3 bits, see alignment E=7.9e-19 PF13545: HTH_Crp_2" amino acids 152 to 224 (73 residues), 61.9 bits, see alignment E=6.9e-21 PF00325: Crp" amino acids 175 to 206 (32 residues), 47.4 bits, see alignment 1.8e-16

Best Hits

KEGG orthology group: K01420, CRP/FNR family transcriptional regulator, anaerobic regulatory protein (inferred from 100% identity to sme:SMa1141)

Predicted SEED Role

"Miscellaneous; Not classified regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Z75 at UniProt or InterPro

Protein Sequence (254 amino acids)

>SMa1141 FNR/CRP family transcriptional regulator (Sinorhizobium meliloti 1021)
MNAQVVSMQDARTRATCSQAFPVADLSSLFARQPVERFAPAQAVFWQGDEATHIFEVTVG
MLRALRLLGDGRRIIVGFLRPGDLLGVSLKERYLYTVEAVSSVELRRFPRRRFEDEVARH
SNLQQQLFSRLRDEMTAAQDQAVLLSRRSAEEKLANFFLLMGQNQNCKQTSIVDLPMTRL
DIADYLGMTIETVSRTITKLANSGVIATPERRSVTVLKMETLRSLADGDESDYWTPSPYR
VRSMHPPVFEGGGA