Protein Info for SMa1126 in Sinorhizobium meliloti 1021

Annotation: Protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 372 transmembrane" amino acids 15 to 33 (19 residues), see Phobius details amino acids 41 to 63 (23 residues), see Phobius details amino acids 98 to 123 (26 residues), see Phobius details amino acids 138 to 158 (21 residues), see Phobius details amino acids 191 to 215 (25 residues), see Phobius details PF02163: Peptidase_M50" amino acids 46 to 120 (75 residues), 59 bits, see alignment E=4.5e-20 amino acids 136 to 191 (56 residues), 32.5 bits, see alignment 5.8e-12 PF00571: CBS" amino acids 232 to 287 (56 residues), 31.3 bits, see alignment 2.1e-11 amino acids 295 to 340 (46 residues), 17.9 bits, see alignment 3.2e-07

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMa1126)

Predicted SEED Role

"Putative zinc metalloprotease MJ0392 (EC 3.4.24.-)" (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Z83 at UniProt or InterPro

Protein Sequence (372 amino acids)

>SMa1126 Protease (Sinorhizobium meliloti 1021)
MGWSLKLGTIAGTEIRIHMTFVLLLVWIWFTHYQIGGAPAAWEGVAFILSVFVCVVLHEF
GHIAAARRFGIKTPDITLLPIGGVARLERNPSEPREELLIAVAGPLVNVVIAALLIAVIG
GVAGLEQLVRPQDPQIDFFVRLAGVNIFLVLFNMIPAFPMDGGRVLRAILAWRWSLERAT
RVAATIGQGTAFVMGVAGLFYSPLLILIAIFVYLAAESEAQSSELQAISVTVGDVMLTEF
GVLQSDARLSEAAELLLATSQNEFPVVDGEGQFAGLLTRDGIIGAMKEGGPNALVGTVMR
TDIPWVYEETALGDSLRVMQTTGAPAAAVVSRSQHPIGIMNYETIGEMLMLRAAVHDFRF
GMLRRSRAGSHG