Protein Info for SMa0717 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 569 PF09339: HTH_IclR" amino acids 21 to 72 (52 residues), 51.1 bits, see alignment 1.4e-17 PF01614: IclR_C" amino acids 90 to 258 (169 residues), 129.2 bits, see alignment E=2e-41 PF08450: SGL" amino acids 293 to 535 (243 residues), 301.6 bits, see alignment E=7e-94

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMa0717)

Predicted SEED Role

"Transcriptional regulator, IclR family / Gluconolactonase family protein" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92ZR8 at UniProt or InterPro

Protein Sequence (569 amino acids)

>SMa0717 hypothetical protein (Sinorhizobium meliloti 1021)
MDDKAGLGGLEDRGAPAGAAALAKGLALLDLIAEAPKPLRFADLQKMSGVPKPTLARMLK
TLMVFRLIRQDETTGAYLLGHRFVELSHRVWDKFDLVSAAIPELDRLASELGETVALCRL
DGQRVVYLEERSSGGLGVLIEVGRRVPVHCTAAGKVLLAFQEPSFARSLAGQITYDRFTP
NTITDSQALEADLVLTRARGYAVSYEEHLAGVNSVAAPIAGRDGVPLGALVVLGPASRLD
SSAIHPAGRELMAAARRITGTVGAVAISSGPRPRTRSGGFSDVQCVLPWGAQLGEAPVWV
EREKRLYWVDILHPAVHRFDPVTGKNESCNVAKLVSAVLPTRNEGLIVASQDGVEHFDFD
RGDFNPFAEPEPGLPENRLNDAKVDPSGRLWVGSMRLDVSRPTGSLYRLTSAGEVTRAGS
GFTVANGLAWSPDSSTFYFVDTVPGIIYAYDFDAREGSIANRRVFVTVPEAEGRPDGLAV
DADGGVWCAIWDGWRVNRYRPDGRLDRAVELPVPRPTSVAFGGDELATLFITSARTRLPA
STLTEAPLSGGIFACNPGARGLPTSLFGV