Protein Info for SMa0380 in Sinorhizobium meliloti 1021

Annotation: hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 660 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF07969: Amidohydro_3" amino acids 85 to 569 (485 residues), 440.5 bits, see alignment E=1.3e-135 PF01979: Amidohydro_1" amino acids 444 to 568 (125 residues), 28.4 bits, see alignment E=1e-10

Best Hits

KEGG orthology group: K07047, (no description) (inferred from 100% identity to sme:SMa0380)

Predicted SEED Role

"Exoenzymes regulatory protein AepA precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q930J2 at UniProt or InterPro

Protein Sequence (660 amino acids)

>SMa0380 hydrolase (Sinorhizobium meliloti 1021)
MATRRSFLGGASSLAFANFFSPAKAADPNQTGVDTMHPDLILHNGRVTTLDRTNPNATAI
AIKDGLFLEVGSDSEVMALAGSGTKIVDLKGKGVLPGLIDNHTHVVRGGLNYNMELRWDG
VRSLADAMDMLKRQVAITPAPQWVRVVGGFTEHQFAEKRLPTIEEINAVAPDTPVFLLHL
YDRALLNGAALRAVGYTRDTPNPPGGEITRDANGNPTGLLLAKPNAGILYSTLAKGPKLP
LDYQVNSTRHFMRELNRLGVTGVIDAGGGFQNYPDDYEVIQKLSDENQMTVRLAYNLFTQ
KPKEEKQDFLNWTQSVKYKQGNDYFRHNGAGEMLVFSAADFEDFRQPRPEMAPEMEGELE
EVLRVLAENRWPWRLHATYDETISRALDVFEKVNKDIPLEGLNWFFDHAETISDRSIDRI
AALGGGIATQHRMAYQGEYFAERYGHGVAEATPPIRRMLDKGVNVSAGTDATRVASYNPW
VSLSWMVTGKTVGGMQLYPRANCLDRETALRMWTEKVTWFSNEEGKKGRIEKGQFADLVV
PDKDFFSCAEDEISFIVSELTMVGGKIVYGAGDFKTLDENEIPPAMPDWSPVRKFGGYAA
WGEPERAGARSLRRTAISTCGCASDCGVHGHDHAGAWTSKLPIADLKGFFGALGCSCWAV