Protein Info for SMa0034 in Sinorhizobium meliloti 1021

Annotation: protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 551 PF00413: Peptidase_M10" amino acids 60 to 158 (99 residues), 25.4 bits, see alignment E=1.8e-09 PF08548: Peptidase_M10_C" amino acids 209 to 372 (164 residues), 36.6 bits, see alignment E=6.3e-13 amino acids 436 to 518 (83 residues), 45.3 bits, see alignment E=1.4e-15 PF00353: HemolysinCabind" amino acids 316 to 342 (27 residues), 19.3 bits, see alignment (E = 1.4e-07) amino acids 334 to 368 (35 residues), 30 bits, see alignment 5.9e-11 amino acids 404 to 439 (36 residues), 30.8 bits, see alignment 3.4e-11 amino acids 432 to 456 (25 residues), 23.5 bits, see alignment (E = 6.5e-09)

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMa0034)

Predicted SEED Role

"Serralysin-like metalloprotease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q931C8 at UniProt or InterPro

Protein Sequence (551 amino acids)

>SMa0034 protease (Sinorhizobium meliloti 1021)
MPAATTYATTGNAYIDGLLGDWKWGIKDFTFSFPTSASFYSAGYGNGEPLKGFAALSGAQ
QAATRAALDQFSSVANVTFTEITESATKHADLRLASSDAPSTAWAYFPSTAAEGGDAWFN
KSSGHYSRPVKGNYAYVTFLHETGHALGLEHAHEGNVMPVNRDSMEYTVMSYRSYVGAST
TTGYTNETWGYAQSLMMYDIAALQHMYGADFTTHSENTTYRWSPTSGEMFVNGMGQGAPG
GNKILLTVWDGGGTDTYDFSNYTTALKVDLRPGEWTTTSAAQLAKLHYDGSKVAIGNIAN
ALQYQGDTRSLIENAKGGAGNDAITGNAAANALWGNGGNDRLIGGDGNDNLAGGAGADRL
DGGNGTDLANYSNATAGMVADLYSPGSNTGEAAGDTYVSIERLYGSAFNDTLRGDNRANL
LNGLAGNDMLNGRDGNDTLIGGNGADRLIGGGGADTFVFQTTAQSAPAFRDVIDDFASGV
DRMDLRSIDASSKAIGDQAFLFIGSSAFHGKAGELNFRSGIVSGDVNGDGLADFQIRVMN
LSALSGSDFLL