Protein Info for SMa0015 in Sinorhizobium meliloti 1021

Annotation: selenocysteine-specific elongation factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 666 TIGR00475: selenocysteine-specific translation elongation factor" amino acids 1 to 629 (629 residues), 429.9 bits, see alignment E=8.9e-133 PF00009: GTP_EFTU" amino acids 2 to 159 (158 residues), 106.4 bits, see alignment E=3.6e-34 PF03144: GTP_EFTU_D2" amino acids 191 to 259 (69 residues), 43.6 bits, see alignment E=8.4e-15 PF09106: SelB-wing_2" amino acids 444 to 499 (56 residues), 55.4 bits, see alignment 1.3e-18 PF21214: SelB_WH_2nd_bact" amino acids 507 to 567 (61 residues), 27.7 bits, see alignment 5.2e-10 PF09107: SelB-wing_3" amino acids 587 to 629 (43 residues), 56.7 bits, see alignment 3.6e-19

Best Hits

KEGG orthology group: K03833, selenocysteine-specific elongation factor (inferred from 100% identity to sme:SMa0015)

Predicted SEED Role

"Selenocysteine-specific translation elongation factor" in subsystem Selenocysteine metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q931D5 at UniProt or InterPro

Protein Sequence (666 amino acids)

>SMa0015 selenocysteine-specific elongation factor (Sinorhizobium meliloti 1021)
MIVGTAGHIDHGKTTLVKALTGVDTDRLKEEKARGITIDLGFAYARFAKDAVTGFVDVPG
HERFIHTMLAGAGGIDYAMLVVAADDGIKPQTLEHLAILDLLGVSRGLVAITKADLADPA
RLENLTDEIGAVLSSTSLRDAEILPVSVAAGQGIELLKERLAAAECATAASAVGGRFRLA
VDRSFTLSGAGTVVTGTVLSGSVGVGDQVTVSPAGRSARVRSIHAQNQRAERGFAGQRCA
LNLAGEGISKDAITRGDMVVDPHLHAPSDRLDADLSVLESETKPIGEWFSARFHHASAET
GIRIVPLEGPLLPGERRRVQLVLDRPIAAAVGDRFILRDVSARRTIGGGRLLDLRAPARK
RRSPERLSYLQAASLSHAGEALAALLDVPPFLVDLDVFARDRALSEAELQNAIRSASAEV
IEGSAVRHALSKRQRAAFSDEVQRVLSAFHVENPDLQGIGRERLRLQVTPRLPPPAFLVA
LRAEQTAGRLVLEGAFVRLPGHEVRLSEKEEELYARILPHLEGEERFRPPRVRDFAEALG
VDEREIRRILKLCARLGRVDQIRHDHFFTRQTTAEMVAIIRQVAANAERGEFSAGLFRDR
VNNGRKVAIEILEFFDRQGVTIRHGDVRRVNPHRLDLYEGPVPEADEGRGSSPVERPDFK
FYRAGS