Protein Info for SM_b21635 in Sinorhizobium meliloti 1021

Annotation: bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 688 TIGR02278: phenylacetic acid degradation protein paaN" amino acids 11 to 682 (672 residues), 1028.3 bits, see alignment E=0 PF00171: Aldedh" amino acids 27 to 507 (481 residues), 206.8 bits, see alignment E=7.2e-65 PF13452: MaoC_dehydrat_N" amino acids 548 to 673 (126 residues), 25.1 bits, see alignment E=2.5e-09 PF01575: MaoC_dehydratas" amino acids 549 to 651 (103 residues), 84.1 bits, see alignment E=9.5e-28

Best Hits

KEGG orthology group: K02618, phenylacetic acid degradation protein (inferred from 100% identity to sme:SM_b21635)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92TG5 at UniProt or InterPro

Protein Sequence (688 amino acids)

>SM_b21635 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase (Sinorhizobium meliloti 1021)
MNVVADRPRRLESYIAGAWMRGSKDGVTLCDAATGAPVALVDSSGIDFAAALAYGREKGG
PALRRMSFHERAMMLKALAQALMERKEEFYALSTATGATRADSWIDIEGGIGTLFSYASK
GRRELPNSHVLLDGDVEALSRDGTFSAQHILTPLQGIAVHINAFNFPCWGMLEKLAPTLL
AGMPAIVKPASQTAYLAELVVRRIVDTGLLPEGALQLVCGSPGDLLDRVGDQDVVTFTGS
ATTGRKLKTHPAIVGNSVRFTMEADSLNAAVLGLDAAPGAEEFGLFVREVAREMTSKAGQ
KCTAIRRVIAPRAHCDALITALGERLAKVPLGDPADENVRMGPLASRDQREEVRARILDL
TTDAEIVAGDPARPQLVSGDAEAGAFLNPVLLYCDSPDAARSVHDVEAFGPVSTVMPYDT
AEEAVDLVRRGRGSLVTSVFTNDPDIARELVIGMAPFHGRVMIGNRLSAKSSTGHGSPLP
GLVHGGPGRAGGGEELGGMRGVRHYMQRTAVQGAPGLVAAVTGRWMEGAPARSGGEHPFR
KSLAELRVGDQIVTETRTVTLEDIEHFAEFTGDTFYAHMDEEAARANPFFDGRVAHGYLV
VSLAAGLFVDPAPGPVLANYGVDGMRFLTPVYPGDTLQVRLTCKEISPRINSDYGEVRWD
CRVTNQTGATVAQYDVLTMVAKTGSGEE