Protein Info for SM_b21595 in Sinorhizobium meliloti 1021

Annotation: sugar uptake ABC transporter substrate-binding protein precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01547: SBP_bac_1" amino acids 43 to 324 (282 residues), 154.2 bits, see alignment E=8.4e-49 PF13416: SBP_bac_8" amino acids 46 to 354 (309 residues), 148.3 bits, see alignment E=3.9e-47

Best Hits

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 100% identity to smk:Sinme_4677)

Predicted SEED Role

"Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE" in subsystem Bacterial Chemotaxis or Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q926G1 at UniProt or InterPro

Protein Sequence (410 amino acids)

>SM_b21595 sugar uptake ABC transporter substrate-binding protein precursor (Sinorhizobium meliloti 1021)
MGIRKYAMLGAFALASVSLPAFSASAEDVTISVWSLDRDIQPAPNLIKDFNKLNTGIKVE
YRQIQFDDVVSEAMRAYSTGQAPDIIAVDNPEHALFASRGAFLDLSEMIAKSSVVKPENY
FKGPLASVTWDGKYYGVPKATNTIALYYNKDMFKAKGLDPNKPPQTWDELVEAARKLTDP
AQNVYGITFSAKANEEGTFQFLPWAQMAGGGYDNINAEGAVKALDVWKTIIDQKLASPDT
LTRSQWDATGTFNSGNAAMAISGPWEIDRMLEEAKFDWGVALLPVPEVGAERSSAMGDFN
WAVFANTEHPEEAFKVLEYFVSQDDRMFKDFGQLPPRSDIAIPATGEPKKDAALQVFVEQ
LKYAKPRGPHPAWPKISKAIQDAIQAALTGQMSSKEALDQAAEKIKAVLG