Protein Info for SM_b21530 in Sinorhizobium meliloti 1021

Annotation: sulfoacetaldehyde acetyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 591 TIGR03457: sulfoacetaldehyde acetyltransferase" amino acids 2 to 582 (581 residues), 1062.3 bits, see alignment E=0 PF02776: TPP_enzyme_N" amino acids 3 to 119 (117 residues), 108.3 bits, see alignment E=3.2e-35 PF00205: TPP_enzyme_M" amino acids 187 to 324 (138 residues), 121.3 bits, see alignment E=3.7e-39 PF02775: TPP_enzyme_C" amino acids 404 to 555 (152 residues), 109.7 bits, see alignment E=1.8e-35

Best Hits

Swiss-Prot: 100% identical to XSC_RHIME: Probable sulfoacetaldehyde acetyltransferase (xsc) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03852, sulfoacetaldehyde acetyltransferase [EC: 2.3.3.15] (inferred from 100% identity to smk:Sinme_4741)

MetaCyc: 76% identical to sulfoacetaldehyde acetyltransferase (Roseovarius nubinhibens ISM)
Sulfoacetaldehyde acetyltransferase. [EC: 2.3.3.15]

Predicted SEED Role

"Sulfoacetaldehyde acetyltransferase (EC 2.3.3.15)" (EC 2.3.3.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.3.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92UW6 at UniProt or InterPro

Protein Sequence (591 amino acids)

>SM_b21530 sulfoacetaldehyde acetyltransferase (Sinorhizobium meliloti 1021)
MKMTTEEAFVKVLQMHGIEHAFGIIGSAMMPVSDLFPKAGIRFWDCAHETNAGMMADGFS
RATGTMSMAIGQNGPGVTGFITAMKTAYWNHTPLLMVTPQAANKTIGQGGFQEVDQMAMF
EEMVCYQEEVRDPSRIPEVLNRVIEKAWRGCAPAQINIPRDFWTQVIDVDLPRIVRFERP
AGGPAAIAQAARLLSEAKFPVILNGAGVVIGNAIQESMALAEKLDAPVCCGYQHNDAFPG
SHRLSVGPLGYNGSKAAMELISKADVVLALGTRLNPFSTLPGYGIDYWPKDAAIIQVDIN
ADRIGLTKKVTVGICGDAKQVAQQILQQLAPAAGDASREERKALVHQTRSAWLQQLSSMD
HEDDDPGTEWNVGARQREPDRMSPRQVWRAIQAVLPKEAIISTDIGNNCAIGNAYPSFEQ
GRKYLAPGMFGPCGYGFPSIVGAKIGCPDVPVVGFAGDGAFGISMNEMTSIGREGWPAIT
MVIFRNYQWGAEKRNTTLWYDNNFVGTELNPNLSYAKVADGCGLKGVTVDTPAALTEALA
KAIEDQAKGITTFVEVVLNQELGEPFRRDAMKKPVAVAGIDRADMRTQRRM