Protein Info for SM_b21435 in Sinorhizobium meliloti 1021

Annotation: allantoate amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 TIGR01879: amidase, hydantoinase/carbamoylase family" amino acids 13 to 409 (397 residues), 339.2 bits, see alignment E=1.7e-105 PF04389: Peptidase_M28" amino acids 66 to 133 (68 residues), 23.2 bits, see alignment E=5e-09 PF01546: Peptidase_M20" amino acids 82 to 408 (327 residues), 85.1 bits, see alignment E=6.5e-28

Best Hits

KEGG orthology group: K01463, [EC: 3.5.1.-] (inferred from 100% identity to sme:SM_b21435)

Predicted SEED Role

"N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87)" in subsystem Hydantoin metabolism (EC 3.5.1.87)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.-

Use Curated BLAST to search for 3.5.1.- or 3.5.1.87

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92U74 at UniProt or InterPro

Protein Sequence (414 amino acids)

>SM_b21435 allantoate amidohydrolase (Sinorhizobium meliloti 1021)
MSFASNTRANIDRFWSTIETSAEIGQGRPGGLARLTLTDDDRRMRDLFVNWCRDAGLCVE
IDELGNIFGRREGSDPSLPPVLIGSHLDTQINGGRFDGIAGVLSGLEVIRTLNDVGHVTR
RPIVVVNWTNEEGARFSPPMVASGCFVGAYDGDWVKELVSDDGARFGAELERIGYNGNKP
CRAGEIDAYYELHIEQGPILDLENRDVGVVTSGYPSYGMRVRFSGKTAHTGPTPMDLRRN
ALVAGARWLTAVDDIGWDFAVGDGKATGARLAAWPNKPGILSDTAQAICDVRHPDAATAR
VMGEKMRRAVFESAARAGCDAVIEDEWFWGGDIFDHAMVEGIRAEAVRMGYDWRDIQSQA
GHDAYFLARHCPTAMIFTPCKGGITHNNEEDCDRDDLAPGLNVLLHAVVARADR