Protein Info for SM_b21424 in Sinorhizobium meliloti 1021

Annotation: esterase or acylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 578 transmembrane" amino acids 153 to 170 (18 residues), see Phobius details TIGR00976: hydrolase CocE/NonD family protein" amino acids 16 to 563 (548 residues), 373.8 bits, see alignment E=9.9e-116 PF02129: Peptidase_S15" amino acids 20 to 297 (278 residues), 230.8 bits, see alignment E=2.5e-72 PF08530: PepX_C" amino acids 335 to 559 (225 residues), 94.3 bits, see alignment E=1.1e-30

Best Hits

KEGG orthology group: K06978, (no description) (inferred from 100% identity to sme:SM_b21424)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92U85 at UniProt or InterPro

Protein Sequence (578 amino acids)

>SM_b21424 esterase or acylase (Sinorhizobium meliloti 1021)
MMHTQSTIRLLDNIDVPMRDGVRLKTDIWLPATEEPCPVLLQRTPYRRETPFGSQYISAL
EFQTALGRGYAVVVQDTRGRYGSEGDFTPFQTEASDGADTIGWLRMQPFCNGSVAMFGAS
YVGATQILALAENPEGLKAIAPQLTTARHGETWMYRGGAVELAFILLWVIESLGPDHLQH
RIAFLPADMRERARALLQTLRESPHAAFERLPVLDDAIIELAPYLADWLDSKAIAGERNR
DRLEWVEKSRAALLVVGGWNDIFVEGSIELFEKARSRWSRGEYMPDRLIIGPWSHGNPTD
WQGREWLGYAASTIDLPEETLRFFDSALEDREPASPVVRYFRSGSNTWHAAPDWPLPDSI
EVSLILDCSRFSLGSTPAEQASASFISDPLKPVPTAGGATFLPGLLLGRNSGPVDQAAIE
ARDDVVIFTGQPLGEDLEVTGLVRARLWVSSSAASCDWTARLCEVGADGGSSGIVDGILR
WSRSRQAGGEPQEVAVRLGHISRLFRKGCRLRLQIASSNFPRFDRNPQSGIPPTLARASD
FIRAEQRIFSGEAFPSRLILPVVTTSYAQAETLSALGR