Protein Info for SM_b21372 in Sinorhizobium meliloti 1021

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 PF00356: LacI" amino acids 14 to 59 (46 residues), 35.2 bits, see alignment 1.7e-12 PF00532: Peripla_BP_1" amino acids 72 to 321 (250 residues), 50.3 bits, see alignment E=4.9e-17 PF13407: Peripla_BP_4" amino acids 74 to 321 (248 residues), 56.4 bits, see alignment E=6.8e-19 PF13377: Peripla_BP_3" amino acids 192 to 351 (160 residues), 74 bits, see alignment E=3.2e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_4761)

Predicted SEED Role

"Ribose operon repressor" in subsystem D-ribose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92UY4 at UniProt or InterPro

Protein Sequence (352 amino acids)

>SM_b21372 LacI family transcriptional regulator (Sinorhizobium meliloti 1021)
MSGDASTVTRQIKTMEDFSEFVGLSRPTVSKYFNDPSSVRKKTRDAIEAAIKQSGFRPNI
FAVNLNRRRTNILGVIVPNSTDPFYMALTRRIEHIADQAGFLAFVLSSDGRPEMEERAIE
TFKSMNVAGAIIAPLGVQSHHQKLSALGQSIPLIYVDSPLDDSSSFVGTDNRQSFRLMVD
YLCRSGGPPCYLGMPPVNNNAMARQDAYVEAMRQLKMKPEVVETTAYASWDFEKFGFDET
LRILSKGGFPTQTVLCANDRVAFGVIAAAFQSGLKVGRDADSDLRVAGHDDHPLSRYTCP
PLTTVAQNYNEIGRLAIELLLFKLGETSGNGEAFREDERILLSAEIMLRGSA