Protein Info for SM_b21357 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 172 transmembrane" amino acids 23 to 44 (22 residues), see Phobius details amino acids 56 to 77 (22 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 119 to 138 (20 residues), see Phobius details PF09990: DUF2231" amino acids 17 to 152 (136 residues), 161.3 bits, see alignment E=7.6e-52

Best Hits

KEGG orthology group: None (inferred from 99% identity to smk:Sinme_4775)

Predicted SEED Role

"Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8)" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange (EC 1.8.1.8)

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.8

Use Curated BLAST to search for 1.8.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92V01 at UniProt or InterPro

Protein Sequence (172 amino acids)

>SM_b21357 hypothetical protein (Sinorhizobium meliloti 1021)
MADRDLLGLAASAKIGGHPIHPMLVPFPIALLVATFICDIVYLANGNSFWADVSMWSLGA
AIVMAALAALAGLTDFLGNARIRAINDAWKHMIGNIVVVLFAIAGFWLRYENGSVEAVWP
WGFLLSLVTVLLLLYTGWKGGELVYHHRVGMDPEAEDGAATPSMTRHRTKHI