Protein Info for SM_b21292 in Sinorhizobium meliloti 1021

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 412 transmembrane" amino acids 17 to 36 (20 residues), see Phobius details amino acids 87 to 109 (23 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 152 to 170 (19 residues), see Phobius details amino acids 176 to 197 (22 residues), see Phobius details amino acids 229 to 246 (18 residues), see Phobius details amino acids 252 to 271 (20 residues), see Phobius details amino acids 283 to 301 (19 residues), see Phobius details PF06181: Urate_ox_N" amino acids 6 to 299 (294 residues), 465.7 bits, see alignment E=3.4e-144

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SM_b21292)

MetaCyc: 72% identical to membrane-bound urate hydroxylase (Agrobacterium fabrum C58)
1.14.99.-

Predicted SEED Role

"FIG137887: membrane protein related to purine degradation"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92VB2 at UniProt or InterPro

Protein Sequence (412 amino acids)

>SM_b21292 membrane protein (Sinorhizobium meliloti 1021)
MYEYAIAWDWLTFAVRWLHVITGIAWIGSSFYFVALDLGLKQRPGMPVGAYGEEWQVHGG
GFYHIQKYLVAPENMPEHLIWFKWESYVTWLSGFGMLALVYYAGADLYLIDPNVLDVSKP
MAIAISLASLGFGWLAYDMICRSPFGNDNTRLMVLLYFILVIVAWGYTQLFTGRAAYLHL
GAFTATIMSANVFFIIIPNQKKVVADLIAGRTPDPALGKQAKQRSTHNNYLTLPVLFLML
SNHYPLAFGTQYNWIIASLVFLMGVTIRHWFNTRHANKGRPTWTWLATVLLFIAIMWLST
VPKVLSHGGEARASTAAEAVVASPDFSKVRDTVLGRCSMCHAREPGWEGIIVPPKGVVLE
ADGDIVAHAREIYLQAGRSHAMPPANVTGITEEERQLIASWYETTVTEGKVQ