Protein Info for SM_b21273 in Sinorhizobium meliloti 1021

Annotation: spermidineputrescine ABC transporter substrate-binding protein precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF13531: SBP_bac_11" amino acids 27 to 284 (258 residues), 42.2 bits, see alignment E=1.7e-14 PF01547: SBP_bac_1" amino acids 36 to 279 (244 residues), 52.3 bits, see alignment E=1.8e-17 PF13416: SBP_bac_8" amino acids 43 to 304 (262 residues), 114.3 bits, see alignment E=1.9e-36 PF13343: SBP_bac_6" amino acids 90 to 304 (215 residues), 58.4 bits, see alignment E=1.6e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_4928)

Predicted SEED Role

"ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q926H0 at UniProt or InterPro

Protein Sequence (340 amino acids)

>SM_b21273 spermidineputrescine ABC transporter substrate-binding protein precursor (Sinorhizobium meliloti 1021)
MKKILIASTALLLIGAHGASAQEKTLTISVYGFAQDAFKELVYDPFEAKCGCKLVVETGN
SVERLAKMEANKANPVVDMAVVSMADALSATRAGLIDKIDTSKLSNFDKLYDIAKDPNGD
GMSIGYTFYATSIVYRSDKVEVTSWADLLGDKLAGHVALPNVTTNQGPPTLYMIGEALGQ
NTPDLKAAIAAVGEKKDDIVTFYVKSSQLVQLMQQEEIWAAPIGRFSWEGFTKMDLPIKW
ATPKEGQTGGMNVMVLAKGSKNQDLALQFMDFWLSTEIQTALAEKLVDSPANKEVKVSPE
IAENLTYGEETVKNLKLIPSAVALDNREAWLSEWNAKVGQ