Protein Info for SM_b21249 in Sinorhizobium meliloti 1021

Annotation: sulfotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 PF00685: Sulfotransfer_1" amino acids 25 to 264 (240 residues), 90 bits, see alignment E=1.7e-29 PF13469: Sulfotransfer_3" amino acids 101 to 197 (97 residues), 30.7 bits, see alignment E=3.8e-11

Best Hits

KEGG orthology group: K01015, alcohol sulfotransferase [EC: 2.8.2.2] (inferred from 100% identity to sme:SM_b21249)

Predicted SEED Role

"putative sulfotransferase protein"

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.8.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92VF3 at UniProt or InterPro

Protein Sequence (280 amino acids)

>SM_b21249 sulfotransferase (Sinorhizobium meliloti 1021)
MASILRRAWRRVEKRVRLTANAAQADSFLISYPKSGRTWFRYVLSHYLATIARVPETIDL
HNMFSIVPNFDLDPVRGMPGYRFREAKDAIPTILVSHLDYRASLFLRRPVIMMVRDPRDV
IVSAYFHATRHKHRFAGTLTEFIKDRDQGMPKMIDYLNGWAAGLSNRAHFVLSYEGLSAD
TDGRTEAVLEFLRCPVDRTALRAAVEAGRFEAMQDRERVEGIPAHDYDRNDVESLRMRRG
KAGGFRDYLDEAQVAEVERLCAADLTVAAKRLVGHTGLNV