Protein Info for SM_b21217 in Sinorhizobium meliloti 1021

Updated annotation (from data): glucosamine kinase (EC 2.7.1.8)
Rationale: Specifically important for utilizing glucosamine
Original annotation: sugar kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 4 to 292 (289 residues), 118.6 bits, E=1.8e-38

Best Hits

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_4979)

Predicted SEED Role

"predicted glucosamine kinase (EC 2.7.1.8)" (EC 2.7.1.8)

MetaCyc Pathways

• chitin derivatives degradation (4/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.8

Sequence Analysis Tools

See Q92VI2 at UniProt or InterPro

Protein Sequence (311 amino acids)

>SM_b21217 glucosamine kinase (EC 2.7.1.8) (Sinorhizobium meliloti 1021)
MRPLAAIGNVNVDLILGPAEPWPKPGTEVIVDHDELRVGGCAGNNALAWDSLGVDYVIAA
NVGNDQFGTWLKEAFGERSRNWPVEAVGTTLSVGITHPDGERTFFTTRGHLPLFSFPEVH
SMLDGNRLRGGYALLSGSFLTDALTLAYDALFDWADAHEIAVALDTGWPLDGWTETNRLR
TLGWLKRCHCALFNEVETTTLTGLSDPAEAALSLKGEMPAEAIVVVKRGPHGALAIDRDG
GTFSVPAPQVQVVDTIGAGDVFNAGFLAALAAEMPLEACLKTGVTIASEAISTLPRRYGK
PLSAFLEESRR