Protein Info for SM_b21214 in Sinorhizobium meliloti 1021

Annotation: 2-deoxyglucose-6-phosphate phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 240 PF00702: Hydrolase" amino acids 31 to 196 (166 residues), 88.4 bits, see alignment E=8.3e-29 PF13419: HAD_2" amino acids 33 to 201 (169 residues), 59.9 bits, see alignment E=3.3e-20 TIGR01549: HAD hydrolase, family IA, variant 1" amino acids 103 to 195 (93 residues), 26.1 bits, see alignment E=1e-09 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 108 to 200 (93 residues), 57 bits, see alignment E=2.5e-19

Best Hits

KEGG orthology group: K01112, [EC: 3.1.3.-] (inferred from 100% identity to sme:SM_b21214)

Predicted SEED Role

"Putative phosphatase YfbT" in subsystem 2-phosphoglycolate salvage

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.-

Use Curated BLAST to search for 3.1.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92V36 at UniProt or InterPro

Protein Sequence (240 amino acids)

>SM_b21214 2-deoxyglucose-6-phosphate phosphatase (Sinorhizobium meliloti 1021)
MCRPAKHVNSKSKGPGLDTSSSAIFTKNFAALLFDMDGTLLNSMAVVERVWGSWALRNGI
DPVALMKIVHGVRAVDTIRALGLPVDPEQEARILAEAEIADVEGIVEIPGAVSFLKTLPP
ERWAIVTSAPLELAARRLEAAGIPVPRHMVTGEDVSVGKPDPQGYLLAAQRLGVRAEDCL
VFEDAPAGVLAGKSAGAEVAVITGAHAAAAEMPHIMLSHYSDVEARLVEDGWLSLHRRRG