Protein Info for SM_b21205 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 transmembrane" amino acids 36 to 57 (22 residues), see Phobius details amino acids 189 to 212 (24 residues), see Phobius details amino acids 238 to 260 (23 residues), see Phobius details amino acids 269 to 292 (24 residues), see Phobius details amino acids 298 to 319 (22 residues), see Phobius details amino acids 330 to 350 (21 residues), see Phobius details amino acids 356 to 376 (21 residues), see Phobius details PF12679: ABC2_membrane_2" amino acids 22 to 348 (327 residues), 53.6 bits, see alignment E=3.1e-18 PF12698: ABC2_membrane_3" amino acids 37 to 376 (340 residues), 166.4 bits, see alignment E=1.5e-52 PF01061: ABC2_membrane" amino acids 189 to 348 (160 residues), 68.7 bits, see alignment E=8.2e-23

Best Hits

Swiss-Prot: 47% identical to YBHS_ECO57: Probable multidrug ABC transporter permease YbhS (ybhS) from Escherichia coli O157:H7

KEGG orthology group: K09686, antibiotic transport system permease protein (inferred from 100% identity to smk:Sinme_4835)

MetaCyc: 47% identical to ABC exporter membrane subunit YbhS (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-366 [EC: 7.6.2.2]

Predicted SEED Role

"ABC transport system, permease component YbhS"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92V46 at UniProt or InterPro

Protein Sequence (384 amino acids)

>SM_b21205 ABC transporter permease (Sinorhizobium meliloti 1021)
MKAESKMAKAYEPAGRARRFAALVRKESYQVIRDPSSILIAFVLPLVLLFLFGYGVSLDT
TRTRVALVVEEATPLTRDLAASFEASRYFSVATGRDRREFEDDLVLGRVRGILVIPAGFA
AEHAAGRHPSVQVIVDGSDPNTANFVQNYAQGAVANWERQRLSEGRSPPPAIAAEQRFWF
NPQLTSRNFLVPGSIAIVMTLVGTLLTSLVVAREWERGTMEAMMATPVSAAELLAGKLLP
YFVLGLTSMTLCVLVAVFLFDVPFRGSVAALYALSATFLMPALGQGLLISAATKNQFLAS
QLALISAFLPAFLLSGFLFEINSMPTVIQWVTYAVPARYLIPSLQTVFLAGDIWPMFARA
IAVMFLIGCMFFALAARSTRKRIG