Protein Info for SM_b21196 in Sinorhizobium meliloti 1021

Annotation: oligopeptide uptake ABC transporter substrate-binding protein precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 532 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00496: SBP_bac_5" amino acids 70 to 452 (383 residues), 323.1 bits, see alignment E=1.3e-100

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 100% identity to smk:Sinme_4845)

Predicted SEED Role

"Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) or Sex pheromones in Enterococcus faecalis and other Firmicutes (TC 3.A.1.5.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7ANR0 at UniProt or InterPro

Protein Sequence (532 amino acids)

>SM_b21196 oligopeptide uptake ABC transporter substrate-binding protein precursor (Sinorhizobium meliloti 1021)
MASLKLNLRAAALIGSLLIGASPALAEAVLHRGNAGEPQTLDQAHTSINIEEFILKDLYE
GLTIYDAAGKIVPGAAETWELSDDGTVYTFKLRADAKWSDGSPVTAEDFAFSFRRVEDPK
TAAEYANILFPIKNAEKVNKGEVPVDQLGVKAVDEKTLEVTLERPTPFFLELLAHQTALP
VSKASVEKNGADFVKPGVMVSNGAFKLTAHVPNDSLTVEKNTNYWDAANVKLDKVIFYPI
DDQAASVRRFEAKEMDLAYNFSADQIERLRTSYGEQVHVSPTLATYYYAFDTRQEPYNDV
RVRRALSMAVDRDFLAKEIYSGSQLPSYSMVPPGIESYGDPAKADFADMSQLDREDKAIE
LMKEAGYGEGGKPLNIEIRYNTNPNHERVATAVADMWKNTFGAKVSLVNLDVSSHYAYLQ
EGGKFNVARAGWVADYADAENFLALSLSTNKTFNYGHFENAEFDALMKKSYEEQDPAARS
KIMHEAETLLMKEQPIAPFLTQADLWLVSERVKGWQDNAPNAHLSKFLSVAE