Protein Info for SM_b21176 in Sinorhizobium meliloti 1021

Annotation: phosphate uptake ABC transporter substrate-binding protein precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR03431: phosphonate ABC transporter, periplasmic phosphonate binding protein" amino acids 1 to 298 (298 residues), 353.4 bits, see alignment E=1e-109 TIGR01098: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein" amino acids 6 to 261 (256 residues), 240.5 bits, see alignment E=2e-75 PF12974: Phosphonate-bd" amino acids 30 to 288 (259 residues), 193.2 bits, see alignment E=5.2e-61

Best Hits

KEGG orthology group: K02044, phosphonate transport system substrate-binding protein (inferred from 100% identity to smk:Sinme_4862)

Predicted SEED Role

"Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1)" in subsystem ABC transporter alkylphosphonate (TC 3.A.1.9.1) (TC 3.A.1.9.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7ANR1 at UniProt or InterPro

Protein Sequence (301 amino acids)

>SM_b21176 phosphate uptake ABC transporter substrate-binding protein precursor (Sinorhizobium meliloti 1021)
MLKKALLSAVALFALVGHAQAEDLKEFRVGIIGGENEADRLRNYQCLVDQLPAAIGVEKV
SLFPAADYDGVIQGLLGGTLDYAELGASGYAKIYLAKADAVEPILTTVQTDGSTGYHSIM
VARKDSGITKLEDLKGKKLGFADPDSTSGYLVPLVTLPEAIGAPVKEYFGETGFGGGHEN
LVLEVVKGTFDAGTTFGSGVGEFKDGYTSGNLRKMVDKGIVDMNDLVELWKSPLIPNGPI
VVRTALNDDMKAKFKQFMMDLPKTDAACFSAIQGGDFTGFVEVNSDFYKPIIDARKATIG
G