Protein Info for SM_b21059 in Sinorhizobium meliloti 1021

Annotation: glucose-1-phosphate cytidylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00483: NTP_transferase
  • amino acids 39 to 122 (84 residues), 37.4 bits, E=1.1e-13

Best Hits

KEGG orthology group: K00978, glucose-1-phosphate cytidylyltransferase [EC: 2.7.7.33] (inferred from 100% identity to sme:SM_b21059)

Predicted SEED Role

"Glucose-1-phosphate cytidylyltransferase (EC 2.7.7.33)" in subsystem dTDP-rhamnose synthesis (EC 2.7.7.33)

MetaCyc Pathways

• CDP-4-dehydro-3,6-dideoxy-D-glucose biosynthesis (2/3 steps found)
• CDP-6-deoxy-D-gulose biosynthesis (3/5 steps found)
• superpathway of CDP-glucose-derived O-antigen building blocks biosynthesis (3/8 steps found)
• streptomycin biosynthesis (3/18 steps found)

KEGG Metabolic Maps

• Nucleotide sugars metabolism
• Starch and sucrose metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.33

Use Curated BLAST to search for 2.7.7.33

Protein Sequence (174 amino acids)

>SM_b21059 glucose-1-phosphate cytidylyltransferase (Sinorhizobium meliloti 1021)
MRRHTNAAPDWSVDLVETGLKTLTGGRIKRLIDWMNNGTFMLTWGDGVSNIDLDELVAFH
RSHGKLATMTAVRPPARYGHIQFDGNRVVEFTEKPQASEGWINGAFFVLEPGVRDYIGGD
EDMFEHAPMQRLASDGQLMAYRHETFWQCMDTLREKHILQTLWDSGNAPWKTWE