Protein Info for SM_b21019 in Sinorhizobium meliloti 1021

Annotation: sugar ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 505 PF00005: ABC_tran" amino acids 31 to 174 (144 residues), 87.9 bits, see alignment E=1e-28 amino acids 278 to 429 (152 residues), 68.8 bits, see alignment E=8.1e-23

Best Hits

KEGG orthology group: K10558, AI-2 transport system ATP-binding protein (inferred from 100% identity to sme:SM_b21019)

Predicted SEED Role

"Autoinducer 2 (AI-2) ABC transport system, fused AI2 transporter subunits and ATP-binding component" in subsystem Autoinducer 2 (AI-2) transport and processing (lsrACDBFGE operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92VV5 at UniProt or InterPro

Protein Sequence (505 amino acids)

>SM_b21019 sugar ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021)
MNRCGMAGSPVAGRVAKLTDVWKSYGAVPVLKGVSLVLHAGEVHALLGGNGAGKSSLMKI
MSGVIASNAGAIEINGRALTHASPALAQKLGLYLVPQEAHILPNQSVLENICLGLAASPR
ALRPRVEQLVAELSVSLDLDVQAAALEIAERQIVEILRGLVRDARVLILDEPTSALTPFE
TSALFQRVRKLQSQGVGIFFISHKLREIREICGTISVLRDGVIVLSGPLDSYSDAVIIDA
MSRVQIADDADKKRVCRKVSQIGKPRLSVRDLSGEGFRDISLDVRAGEILGLAGVVGAGR
TEFAETLFGLRPQMGGSVVFDGAELKKRSPRICIDLGLVYLPEDRQQHGLFLEAPLSWNV
SSYLVHRLPFFLRPGAERKVFDGFRASMGIKCTGADQEARGLSGGNQQKVLLAKCLSARP
KVLILDEPTRGVDVAARNDLYDVIRRLAADGVAIILISSDFHEIEQLADRVEIMAFGQSG
GKLTDQISVDAIARLAFGASEGRHA