Protein Info for SM_b21018 in Sinorhizobium meliloti 1021

Annotation: sugar ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 37 to 59 (23 residues), see Phobius details amino acids 71 to 102 (32 residues), see Phobius details amino acids 109 to 131 (23 residues), see Phobius details amino acids 151 to 177 (27 residues), see Phobius details amino acids 208 to 232 (25 residues), see Phobius details amino acids 245 to 273 (29 residues), see Phobius details amino acids 286 to 305 (20 residues), see Phobius details PF02653: BPD_transp_2" amino acids 42 to 301 (260 residues), 139 bits, see alignment E=8.5e-45

Best Hits

Swiss-Prot: 53% identical to LSRC_SALTI: Autoinducer 2 import system permease protein LsrC (lsrC) from Salmonella typhi

KEGG orthology group: K10556, AI-2 transport system permease protein (inferred from 99% identity to smk:Sinme_5081)

MetaCyc: 54% identical to Autoinducer-2 ABC transporter membrane subunit LsrC (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-454 [EC: 7.6.2.13]

Predicted SEED Role

"Autoinducer 2 (AI-2) ABC transport system, membrane channel protein LsrC" in subsystem Autoinducer 2 (AI-2) transport and processing (lsrACDBFGE operon)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92VV6 at UniProt or InterPro

Protein Sequence (343 amino acids)

>SM_b21018 sugar ABC transporter permease (Sinorhizobium meliloti 1021)
MLDLFSRNRVATLILVLAVAYAAIGTAAPGYLSGATASVVVSNSLVLMLISLGTMMVILT
RNIDVSSGSVLGLSAAVLGLSLTAGVSLPLAIAFCLATGAVAGAFNGLMVAYLGIPSIVA
TLGTLGLYRGIMLVLTGGRWIEDLPQGLKALAANLGFGFSVLTIVVLALVALAWIVLRRT
RFGRNFYAVGDNRAAAHHLGVPVKLVQFSAFVATGVCAALAGLVFAAQIGFIPNQAGNGI
ELKAIAVNVLGGVSLLGGTGSVAGVFTAVIFITSIDSALVFLKIPAYWNDFIAGAILLSV
LLLDGRIRQIIDRRIRARRYGVHERGPTQSRETTTARNVEASR