Protein Info for SM_b20999 in Sinorhizobium meliloti 1021

Annotation: transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 420 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 62 to 82 (21 residues), see Phobius details amino acids 89 to 115 (27 residues), see Phobius details amino acids 141 to 164 (24 residues), see Phobius details amino acids 209 to 228 (20 residues), see Phobius details amino acids 247 to 268 (22 residues), see Phobius details amino acids 314 to 331 (18 residues), see Phobius details amino acids 336 to 360 (25 residues), see Phobius details PF05992: SbmA_BacA" amino acids 84 to 397 (314 residues), 550.3 bits, see alignment E=1.7e-169 PF06472: ABC_membrane_2" amino acids 96 to 287 (192 residues), 40.8 bits, see alignment E=1.8e-14

Best Hits

Swiss-Prot: 100% identical to BACA_RHIME: Bacteroid development protein BacA (bacA) from Rhizobium meliloti (strain 1021)

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_4593)

MetaCyc: 66% identical to peptide antibiotic/peptide nucleic acid transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-205A

Predicted SEED Role

"Bacteroid development protein BacA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q08120 at UniProt or InterPro

Protein Sequence (420 amino acids)

>SM_b20999 transporter (Sinorhizobium meliloti 1021)
MFQSFFPKPKLFFISSAVWSLLAVLAWYAGGRDIGAYLGLPPLPPGQEPVIGVSVFWSTP
FLWFYIYYAVVAGLFAAFWFAYSPHRWQYWSVLGTALIIFNTYFSVQVSVAINAWYGPFY
DLIQQALARTAPVTAGQLYSGMIGFSGIAFVAVTVGVLNLFFVSHYIFRWRTAMNEFYVA
HWPRLRHVEGASQRVQEDTMRFSSTVERLGVGLVSSIMTLIAFLPVLFKFSEQVNVLPIV
GEIPHALVWAAVFWSVFGTVFLAAVGIKLPGLEFRNQRVEAAYRKELVYGEDHEDRADPI
TLAQLFDNVRRNYFRLYFHYMYFNIARIFYLQADNLFGTFVLVPAIVAGKLTLGVMNQVL
NVFGQVRESFQYLVNSWTTIVELLSIYKRLKAFESVLVDEPLPEIDRQFIDAGGKEELAL