Protein Info for SM_b20992 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13454: NAD_binding_9
  • amino acids 23 to 178 (156 residues), 114.1 bits, E=3e-37

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SM_b20992)

Predicted SEED Role

"Hydroxyacylglutathione hydrolase (EC 3.1.2.6)" in subsystem Glutathione: Non-redox reactions or Methylglyoxal Metabolism (EC 3.1.2.6)

MetaCyc Pathways

• methylglyoxal degradation VIII (3/3 steps found)
• superpathway of methylglyoxal degradation (6/8 steps found)
• methylglyoxal degradation I (2/3 steps found)

KEGG Metabolic Maps

• Pyruvate metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.2.6

Use Curated BLAST to search for 3.1.2.6

Sequence Analysis Tools

See Q92UL0 at UniProt or InterPro

Protein Sequence (467 amino acids)

>SM_b20992 hypothetical protein (Sinorhizobium meliloti 1021)
MTVLGLFADRSAAAASSSKPEIAIVGRGFSGIMMAIALMKSMRGSFHLTMYDPHPSISGG
QAFSAAQRCEILNSRVRDLSVAAGQPDDFNDWLCANDEFRTAVPAAIPGFRQIFVPKGIF
SDYVHQRFSEALARRSDITVRFSHEQVTGLRKLASGRFSLVRDGGHDACDIVILATGFGV
HPRDLEVSDEERPLMRTRRLVDPRHAVLLGSGIRVVDQLFQMRDNGYAGKVTLVSRHGFL
PQAHTQLAAAPSFPVDPMPQGLRRIVRFVRQACAEAEAKGQSWQSAMNGLRRRARSLWQS
LSAQEKRQFNRHLRAIYDSHRNRLPAAVHARLQQELAEGRTVLRRGRAGRRLPEGIMVRW
AGQHAEELLRADQVIECRCSAPDLGTPLLRSLFAGGLAEPDELELGIAVSPTGEVLSPCA
RTPNLFAIGPLGLGSLPDIDLVPEIVTQTYAAARLIATGKRLALKAG