Protein Info for SM_b20944 in Sinorhizobium meliloti 1021

Annotation: polysaccharide polymerase, Wzy protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 37 to 55 (19 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 89 to 106 (18 residues), see Phobius details amino acids 118 to 136 (19 residues), see Phobius details amino acids 156 to 174 (19 residues), see Phobius details amino acids 179 to 198 (20 residues), see Phobius details amino acids 204 to 223 (20 residues), see Phobius details amino acids 230 to 251 (22 residues), see Phobius details amino acids 328 to 348 (21 residues), see Phobius details amino acids 360 to 376 (17 residues), see Phobius details amino acids 382 to 400 (19 residues), see Phobius details PF04932: Wzy_C" amino acids 188 to 336 (149 residues), 70 bits, see alignment E=1e-23

Best Hits

Swiss-Prot: 100% identical to EXOQ_RHIME: Exopolysaccharide production protein ExoQ (exoQ) from Rhizobium meliloti (strain 1021)

KEGG orthology group: None (inferred from 100% identity to sme:SM_b20944)

MetaCyc: 100% identical to O-antigen ligase family protein (Sinorhizobium meliloti 1021)
RXN-22295 [EC: 2.4.99.26]

Predicted SEED Role

"Exopolysaccharide production protein ExoQ"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.99.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q02729 at UniProt or InterPro

Protein Sequence (435 amino acids)

>SM_b20944 polysaccharide polymerase, Wzy protein (Sinorhizobium meliloti 1021)
MRISKASLVRPGANEVYGIFALALSLFVFAYSARFGQVSILAYYGLWLPLVLVDYRKVLG
NYASYLWIFAFTIFACITIFWSAAPSLSLRTGIQYLSHVVCALIAMRTIDIRTLTRGMIA
GAAIVLLYSLLFGTYHYDPLDGTYSFVGAFASKNQLGFYASLGIYFAFAAVFVLGEKGLW
MGAAGGAGLLAAYCLLTSQSATSVLTTAAVIGLCLGMRAITALRPASRKLLFIAASVFGG
VAAVAMIYAGGVDLILGAFGKDSTLTGRTYLWQQGIEAAKVSPLVGVGYQAYWVQGFSEA
ERLWEEFYIGSRAGFHFHNTFIEAVVETGLIGLILLTMVLVTAFFGQLKRLLSEDRDPES
MVLFGVGALLFVRAFVEIDILTPYHVGSFLLYFTAGKLTIPRRRRAATLLWPAGLDPAPY
GRTFGPMIPRPGDSR