Protein Info for SM_b20904 in Sinorhizobium meliloti 1021

Annotation: sugar uptake ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 261 PF00005: ABC_tran" amino acids 25 to 175 (151 residues), 111.7 bits, see alignment E=4.5e-36

Best Hits

Swiss-Prot: 41% identical to FRCA_RHIML: Fructose import ATP-binding protein FrcA (frcA) from Rhizobium meliloti

KEGG orthology group: K10545, D-xylose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 100% identity to smk:Sinme_4518)

Predicted SEED Role

"D-xylose transport ATP-binding protein XylG" in subsystem Xylose utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92UD4 at UniProt or InterPro

Protein Sequence (261 amino acids)

>SM_b20904 sugar uptake ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021)
MTEQRTPLVEMKNISISFGGIHAVDDASVDLYPGEVVALLGHNGAGKSTLIKILSGAYKR
DAGEILINGEPAEINNPRDAKKYGIETIYQTLAVADNVDAAANLYLGRELRTPWGTLDDV
AMEAKAREVMGRLNPNFQRFKEPVKALSGGQRQSVAIARAILFDARILIMDEPTAALGPQ
ETAQVGELIKQLKREGIGIFLISHDIHDVFDLADRVSVMKNGQVVGHARTEDVTKDEVLG
MIIMGKVPPKAIPGPGAMQMA