Protein Info for SM_b20784 in Sinorhizobium meliloti 1021

Annotation: branched-chain amino acid ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 PF00005: ABC_tran" amino acids 21 to 161 (141 residues), 103.9 bits, see alignment E=1.2e-33

Best Hits

Swiss-Prot: 37% identical to LIVF_SALTY: High-affinity branched-chain amino acid transport ATP-binding protein LivF (livF) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01996, branched-chain amino acid transport system ATP-binding protein (inferred from 100% identity to sme:SM_b20784)

MetaCyc: 33% identical to lipopolysaccharide transport system ATP binding protein LptB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-237 [EC: 7.5.2.5]

Predicted SEED Role

"Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92TN4 at UniProt or InterPro

Protein Sequence (238 amino acids)

>SM_b20784 branched-chain amino acid ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021)
MPAAPLEVDNLSAGYGPTRVLEGISFSVPAGARLAVLGRNGMGKTTLLATLAGQTRRYEG
RIRIGDANVTALPSASRALKGLGFVPQARCVFPSLTVEENLFVGLKGRPKTALSEAYEMF
PRLYERRRNLGSQLSGGEQQMLSTARSILGRPSVLLLDEPLEGLAPVICEELMKAFAELA
KTGGMTILLVEQRIQSALDFADRVIILERGRLAWSGTPEALAKEHATVERLLGVGGLH