Protein Info for SM_b20718 in Sinorhizobium meliloti 1021

Annotation: sugar uptake ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 PF00005: ABC_tran" amino acids 30 to 177 (148 residues), 104.6 bits, see alignment E=7.1e-34 amino acids 278 to 431 (154 residues), 65.6 bits, see alignment E=7.6e-22

Best Hits

Swiss-Prot: 44% identical to RBSA_CHRVO: Ribose import ATP-binding protein RbsA (rbsA) from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)

KEGG orthology group: K10441, ribose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 100% identity to smk:Sinme_4309)

Predicted SEED Role

"D-xylose transport ATP-binding protein XylG" in subsystem Xylose utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92TS3 at UniProt or InterPro

Protein Sequence (508 amino acids)

>SM_b20718 sugar uptake ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021)
MNPETVDAARVVLEARRISKSFSGVQVLFSVNFELRAGEIHALMGENGAGKSTLVKILSG
FEQPSSGEVLLDGQPVTLPANGAAEALGIVIIHQEFNLAEHLTVAESLFLGREVTRFGVL
DRKYMRAETRRVLDLLGCHVDANALIGSLSIAEKQMVEIAKAISRDARIVFMDEPTAVLS
REETNFLFRQVRKLRDRGTSFVFVSHKLDEVIELTDRVTVLRDGQWVKTAATSMLDGESI
AQLMVGREMSSLFPAKKEPNVDEEVVLRVDAVSTDYVQDARFEVRKGEILGFSGMIGSGR
TELMEAVAGLRPRLSGEVTIRGETVPSGDVHAANRRGLAYMTKDRKAKGLLLNSGMTANL
TLQSLGRHARIGYLSPASEAAALKRARRRFDIRVRDGNVVARRMSGGNQQKLLLAKVMET
EPDIIIIDEPTRGIDVGTKQQIYHFISALARDGRSIIVVSSEMPEVIGLCTRVAVMREGR
IVGMLEGDEISEQEIMRYAAGLKKMAAA