Protein Info for SM_b20704 in Sinorhizobium meliloti 1021

Annotation: glycogen synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 486 TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 1 to 475 (475 residues), 529.6 bits, see alignment E=3.5e-163 PF08323: Glyco_transf_5" amino acids 2 to 235 (234 residues), 252.6 bits, see alignment E=8.8e-79 PF13439: Glyco_transf_4" amino acids 73 to 222 (150 residues), 31.6 bits, see alignment E=3.2e-11 PF00534: Glycos_transf_1" amino acids 291 to 436 (146 residues), 44.5 bits, see alignment E=2.5e-15 PF13692: Glyco_trans_1_4" amino acids 292 to 436 (145 residues), 34.7 bits, see alignment E=4.2e-12

Best Hits

Swiss-Prot: 100% identical to GLGA2_RHIME: Glycogen synthase 2 (glgA2) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 100% identity to sme:SM_b20704)

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.21

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P58394 at UniProt or InterPro

Protein Sequence (486 amino acids)

>SM_b20704 glycogen synthase (Sinorhizobium meliloti 1021)
MQILSVTAEIFPLVKTGGLADVAGSLPKALRAHGIHTRSFVPGYPGVMRALSDATPVAEF
ESLFGERATLIAARAHGLDLFVLDAPAFYDRQGALYVDRHGRDYADNWKRFAAFSLVASQ
IARGLVPNWRPHIIHAHDWHAAMSLLYLKYAGDDTIPRVLTVHNLAFQGQFPAHYFPELG
LPAEAYSIDGVEYYGDIGFLKGGLQAADAITVVSPTYAREIMSPAFGMGLEGVMNERHAD
VVGIVNGIDLEVWDPSSDPCIEHHYSARVPLRRLPNRQVLLRHFGLPDTCGPIFASVNRL
TWQKGMDLLAATAGEIVKNGGTLIIHGQGEEKLEAAFMDLMRRFPQNISVSIGYDEHLAH
RIHAGADAMLVPSRFEPCGLTQLYALRYGCVPVVARTGGLSETIIDANDAALHAHVATGI
QFAPIDEDGLRHALRRTFRLYRLRRVWEGLRRQGMKTDCSWHRSAARYADLYSELLNPDM
RLVGSA