Protein Info for SM_b20595 in Sinorhizobium meliloti 1021

Annotation: cell division protein FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 611 PF17854: FtsK_alpha" amino acids 99 to 199 (101 residues), 100.3 bits, see alignment E=9.1e-33 PF01580: FtsK_SpoIIIE" amino acids 208 to 426 (219 residues), 245.3 bits, see alignment E=7.6e-77 PF09397: FtsK_gamma" amino acids 536 to 595 (60 residues), 87.5 bits, see alignment 5.7e-29

Best Hits

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 100% identity to sme:SM_b20595)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92TK5 at UniProt or InterPro

Protein Sequence (611 amino acids)

>SM_b20595 cell division protein FtsK (Sinorhizobium meliloti 1021)
MVECRRPEPATAEPVTAEPQDIAAEPAAAEAAALPAHQFVETPAPALAEPAIVPASEPAP
EAPVTRAAITMPAVIQRSSPSLPPIGAIEPLQGGDAYEFPSKELLQEPPQGQGFFMTQEQ
LEQNAGLLESVLEDFGVKGEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIARSMSAL
SARVAVVPGRNVIGIELPNATRETVYFRELIESGDFQKTGCKLALCLGKTIGGEPVIAEL
AKMPHLLVAGTTGSGKSVAINTMILSLLYRLKPEECRLIMVDPKMLELSVYDGIPHLLTP
VVTDPKKAVMALKWAVREMEDRYRKMSRLGVRNIDGYNQRAAAAREKGAPILATVQTGFE
KGTGEPLFEQQEMDLSPMPYIVVIVDEMADLMMVAGKEIEGAIQRLAQMARAAGIHLIMA
TQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLLGQGDMLHMAGGGRIAR
VHGPFVSDQEVEHVVAHLKTQGRPEYLETVTADEEEEEVEEDQGAVFDKSAIAAEDGNEL
YDQAVKVVLRDKKCSTSYIQRRLGIGYNRAASLVERMEKDGLVGPANHVGKREIIYGNRD
NAPKPESDDLD