Protein Info for SM_b20498 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01791: DeoC
  • amino acids 18 to 250 (233 residues), 219.6 bits, E=2.3e-69

Best Hits

KEGG orthology group: K01623, fructose-bisphosphate aldolase, class I [EC: 4.1.2.13] (inferred from 100% identity to smk:Sinme_5269)

Predicted SEED Role

"COG1830: DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes"

MetaCyc Pathways

• photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (22/26 steps found)
• superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass (22/26 steps found)
• superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle (19/22 steps found)
• Calvin-Benson-Bassham cycle (12/13 steps found)
• gluconeogenesis I (12/13 steps found)
• formaldehyde assimilation III (dihydroxyacetone cycle) (11/12 steps found)
• glycolysis III (from glucose) (10/11 steps found)
• superpathway of glycolysis and the Entner-Doudoroff pathway (14/17 steps found)
• 1-butanol autotrophic biosynthesis (engineered) (21/27 steps found)
• homolactic fermentation (10/12 steps found)
• glycolysis II (from fructose 6-phosphate) (9/11 steps found)
• ethene biosynthesis V (engineered) (19/25 steps found)
• glycolysis IV (8/10 steps found)
• oxygenic photosynthesis (13/17 steps found)
• pentose phosphate pathway (non-oxidative branch) II (5/6 steps found)
• glycolysis I (from glucose 6-phosphate) (10/13 steps found)
• formaldehyde assimilation II (assimilatory RuMP Cycle) (7/9 steps found)
• sucrose biosynthesis I (from photosynthesis) (7/9 steps found)
• gluconeogenesis III (9/12 steps found)
• superpathway of anaerobic sucrose degradation (14/19 steps found)
• superpathway of N-acetylneuraminate degradation (16/22 steps found)
• superpathway of hexitol degradation (bacteria) (13/18 steps found)
• sedoheptulose bisphosphate bypass (1/2 steps found)
• glycolysis VI (from fructose) (7/11 steps found)
• glycolysis V (Pyrococcus) (6/10 steps found)
• 1,3-propanediol biosynthesis (engineered) (5/9 steps found)
• sucrose degradation V (sucrose α-glucosidase) (2/5 steps found)
• hexitol fermentation to lactate, formate, ethanol and acetate (12/19 steps found)
• gluconeogenesis II (Methanobacterium thermoautotrophicum) (7/18 steps found)
• Methanobacterium thermoautotrophicum biosynthetic metabolism (20/56 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of alkaloids derived from terpenoid and polyketide
• Biosynthesis of phenylpropanoids
• Biosynthesis of plant hormones
• Biosynthesis of terpenoids and steroids
• Carbon fixation in photosynthetic organisms
• Fructose and mannose metabolism
• Glycolysis / Gluconeogenesis
• Pentose phosphate pathway

Isozymes

Compare fitness of predicted isozymes for: 4.1.2.13

Use Curated BLAST to search for 4.1.2.13

Sequence Analysis Tools

See Q92W65 at UniProt or InterPro

Protein Sequence (280 amino acids)

>SM_b20498 hypothetical protein (Sinorhizobium meliloti 1021)
MRTNSKVRMNRLFNRGRCLDVAIDHGVCNEPSFLSGLENMETVVKALTAAAPDAIQMNYG
QADLLQDLPGKDKPALVMRIDMGNPYNRIRHRDMWAVLQNEAEPLIGALAMDAACVVVNL
FMLPDEPDLFRQCVQNIARVRADCDKYRMPLMIEPLVMQPVTEHGGYMVDGDADKIVTLT
RLAREMGADIVKADPTNDVDEFHRVVEAARCPVLVRGGGKEDLRSVLDKSAALMKQGAMG
MVYGRNIYQHSNPKAVVRALMAIVHDNASGEEAFALYRQS