Protein Info for SM_b20467 in Sinorhizobium meliloti 1021

Annotation: sensor kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 607 transmembrane" amino acids 59 to 77 (19 residues), see Phobius details amino acids 89 to 109 (21 residues), see Phobius details amino acids 121 to 139 (19 residues), see Phobius details amino acids 142 to 161 (20 residues), see Phobius details amino acids 163 to 185 (23 residues), see Phobius details amino acids 193 to 214 (22 residues), see Phobius details PF07730: HisKA_3" amino acids 403 to 466 (64 residues), 48.4 bits, see alignment E=1.1e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SM_b20467)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92W96 at UniProt or InterPro

Protein Sequence (607 amino acids)

>SM_b20467 sensor kinase (Sinorhizobium meliloti 1021)
MRVPRGFLRRGFNLRKWYTTLKGRMAAETGWAAALFEGAPAIATSRQTWMNTFRARSDSV
IAVARILLAIGSLWITWIDATIRPGRSDLVFWFLVIYLLYAIAAAHFVWKAQVHRVRGTF
IRHLIDVSSLVILAFLADRVSGPVFMLIPFVQLAATLHWLWRGALWTGSVAVAILIYLAL
SNTVWPFSSDADAAVALSFILFLVTATILLTWLGTHQEAVRSELLRLVEGTPSASDGLEW
PAEAALEYAVQVARVPRALLIWSDGDEPWTNLAIWESGVCAVRHLSPATYLPWTPEALEH
ASLLVIDAKRSRALVHRGGGRFDRWRGDGLPVSPALVAEFSIASAISVQFQASDVEARLF
LLDPPALTIDGVALAEIVADRLKTLFEQTILLRRLSDAAAFEERVKIGRDIHDGVLQALA
GTSLQLQTLRSSREYHEIDERLMAIQAMLSEEQTDLRALIRRLEPGSGRHASDSRLALRL
GALAQRLRQQWSIEFRFVLYPEDLRLPVAMIDELMHMIAEATANAARHGNARTLEARIRR
DDGIVTLTLDDDGIGFGFDRRLEHAELETSKCGPRSLRERVSMSGGNLSIDKVDQWTRIT
IKIPAHS