Protein Info for SM_b20460 in Sinorhizobium meliloti 1021

Annotation: cellulose synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 621 transmembrane" amino acids 32 to 50 (19 residues), see Phobius details amino acids 63 to 86 (24 residues), see Phobius details amino acids 362 to 384 (23 residues), see Phobius details amino acids 396 to 413 (18 residues), see Phobius details amino acids 433 to 452 (20 residues), see Phobius details amino acids 477 to 497 (21 residues), see Phobius details amino acids 506 to 528 (23 residues), see Phobius details amino acids 540 to 559 (20 residues), see Phobius details PF13641: Glyco_tranf_2_3" amino acids 101 to 332 (232 residues), 49 bits, see alignment E=1.1e-16 PF13506: Glyco_transf_21" amino acids 190 to 332 (143 residues), 48.8 bits, see alignment E=9.2e-17 PF13632: Glyco_trans_2_3" amino acids 195 to 397 (203 residues), 59.9 bits, see alignment E=4.8e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SM_b20460)

Predicted SEED Role

"Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12)" (EC 2.4.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.12

Use Curated BLAST to search for 2.4.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92WA2 at UniProt or InterPro

Protein Sequence (621 amino acids)

>SM_b20460 cellulose synthase (Sinorhizobium meliloti 1021)
MTVLSTNGPTRISEDGEPRLVPVLTRERRMEFLLGAGLWVAALVHFWAWWLEPRHHVDAL
GSTIVTAVLAWVTLLPAYFIAVFYGALKPNGPLRLPAGSRIAMVVTKAPSEPFSVVAETL
EAMLAQDVPHDTWLADEDPSEATLDWCRSHGVLVSTRKGREDYHRATWPRRTRCKEGNLA
FFYDHYGYDRYDFVAQLDADHVPAPGYLFEMLRPFADQDVGYVSAPSICDRNASESWSAR
GRLYAEASMHGALQAGYNGGLAPLCIGSHYAVRTAALKEIGGLGPELAEDHSTTLMMNAA
GWRGIHALDAIAHGDGPRTFADLVTQEFQWSRSLVMLLLQYSPRLVGRLPLRLKFQFLFS
QLWYPLFACFMALMFAMPIIALARGETFVAVTYPEFLAYFAPLSIILVLLAYRWRSTAAF
RPYDAKILSWECMLFLFARWPWALAGTLAALRDWITGSFVDFRVTPKGSSEVDPLPLRVL
APYFFLAVAAVLPVLFVDDAANAKGFYLFAILNAAIYCLLLLVIVLRHSRENAVGTASRF
YRPAIGAGLLAIVALPGIATAEHGKDGLEALAWGSGHLRLFEERYAVAGAGQGGTALRKI
VFRPRWISAPAEQRDGNLERG