Protein Info for SM_b20408 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 PF08882: Acetone_carb_G" amino acids 46 to 157 (112 residues), 162.6 bits, see alignment E=1.8e-52

Best Hits

Swiss-Prot: 47% identical to ACXC_XANP2: Acetone carboxylase gamma subunit (acxC) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)

KEGG orthology group: K10856, acetone carboxylase, gamma subunit [EC: 6.4.1.6] (inferred from 100% identity to sme:SM_b20408)

MetaCyc: 47% identical to acetone carboxylase gamma subunit (Xanthobacter autotrophicus Py2)
Acetone carboxylase. [EC: 6.4.1.6]

Predicted SEED Role

"Acetone carboxylase, gamma subunit (EC 6.4.1.6)" (EC 6.4.1.6)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 6.4.1.6

Use Curated BLAST to search for 6.4.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92WE6 at UniProt or InterPro

Protein Sequence (165 amino acids)

>SM_b20408 hypothetical protein (Sinorhizobium meliloti 1021)
MTEYSKEVINDLVNGTLPWPQTRRIMSAYKDHDRFFKYLAVLQDRVAWSDPILLPVGDRL
FICDSAEGRVARCECGYSFGDYRRNWKLNAVINVRDTEESLREIYPNSDIPDPRWMEIRE
FFCPECAHLHEVEAAAPGYPIVHDFEPDLEGFYRDWLGKPLKDLS